Biochemistry
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Cryo-EM structures reveal that RFC recognizes both the 3’- and 5’-DNA ends to load PCNA onto gaps for DNA repair
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A Novel Y-Shaped, S-O-N-O-S-Bridged Crosslink between Three Residues C22, C44, and K61 Is a Redox Switch of the SARS-CoV-2 Main Protease
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Comprehensive analysis of the human ESCRT-III-MIT domain interactome reveals new cofactors for cytokinetic abscission
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Dynamics of allosteric regulation of the phospholipase C-γ isozymes upon recruitment to membranes
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Hypertrophic cardiomyopathy mutations in the pliant and light chain-binding regions of the lever arm of human β-cardiac myosin have divergent effects on myosin function
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Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA
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Antibacterial potency of Type VI amidase effector toxins is dependent on substrate topology and cellular context
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SARS-CoV-2 spike variants differ in their allosteric response to linoleic acid
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The Free Fatty Acid-Binding Pocket is a Conserved Hallmark in Pathogenic β-Coronavirus Spike Proteins from SARS-CoV to Omicron
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Target binding triggers hierarchical phosphorylation of human Argonaute-2 to promote target release
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