Biochemistry
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Allosteric mechanism of signal transduction in the two-component system histidine kinase PhoQ
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Heavy isotope labeling and mass spectrometry reveal unexpected remodeling of bacterial cell wall expansion in response to drugs
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Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism
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Disintegration promotes proto-spacer integration by the Cas1-Cas2 complex
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Cryo-EM Structures of CTP Synthase Filaments Reveal Mechanism of pH-Sensitive Assembly During Budding Yeast Starvation
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Allosteric cooperation in ß-lactam binding to a non-classical transpeptidase
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Assessing target engagement using proteome-wide solvent shift assays
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Efficient incorporation and template-dependent polymerase inhibition are major determinants for the broad-spectrum antiviral activity of remdesivir
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Rapid and Effective Inactivation of SARS-CoV-2 by a Cationic Conjugated Oligomer with Visible Light: Studies of Antiviral Activity in Solutions and on Supports
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Variable inhibition of unwinding rates of DNA catalyzed by the SARS-Cov-2 (COV19) helicase nsp13 by structurally distinct single DNA lesions
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