Bioinformatics
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GTestimate: Improving relative gene expression estimation in scRNA-seq using the Good-Turing estimator
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Deep Learning Reveals Endogenous Sterols as Allosteric Modulators of the GPCR-Gα Interface
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Convolutional Neural Networks and Outline Analyses for Archaeobotanical Studies of Domestication and Subspecific Identification
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Subtle methodological variations substantially impact correlation test results in ecological time series
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Decoding molecular mechanisms for loss-of-function variants in the human proteome
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Cellpose-SAM: superhuman generalization for cellular segmentation
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Translational buffering tunes gene expression in mice and humans
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MerQuaCo: a computational tool for quality control in image-based spatial transcriptomics
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From Mechanistic Interpretability to Mechanistic Biology: Training, Evaluating, and Interpreting Sparse Autoencoders on Protein Language Models
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The Implications of Alternative Splicing Regulation for Maximum Lifespan
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