Biophysics
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Tau hyperphosphorylation impairs cooperative binding to microtubules and perturbs organelle trafficking in neurons
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Multi-barrier unfolding of the double-knotted protein, TrmD–Tm1570, revealed by single-molecule force spectroscopy and molecular dynamics
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Bifunctional Architecture Enables Substrate Catalysis and Channeling in Paracoccus TMAO Demethylase
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Insights into substrate binding and utilization by hyaluronan synthase
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Pulsed laser lensing for phase modulation in electron microscopy
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Unraveling the Molecular Mechanisms of ABHD5 Membrane Targeting
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Conformational Changes of the ABC Transporter BmrA Depend on Membrane Curvature
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In silico design and validation of high-affinity RNA aptamers for SARS-CoV-2 comparable to neutralizing antibodies
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Invasive cancer cells soften collagen networks and disrupt stress-stiffening via volume exclusion, contractility and adhesion
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Stall force measurement of the kinesin-3 motor KIF1A using a programmable DNA origami nanospring
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