Cancer Biology
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MDM2 stabilization of Notch intracellular domain upon DNA damage plays a major role in non-small cell lung carcinoma response to platinum chemotherapy
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Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape
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Resistance to PSEN1-selective γ-secretase inhibitors in T-cell acute lymphoblastic leukemia
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The DBD-α4 helix of EWSR1::FLI1 is required for GGAA microsatellite binding that underlies genome regulation in Ewing sarcoma
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Aging represses lung tumorigenesis and alters tumor suppression
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Patient-derived xenografts and single-cell sequencing identifies three subtypes of tumor-reactive lymphocytes in uveal melanoma metastases
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NPRL2 gene therapy induces effective antitumor immunity in KRAS/STK11 mutant anti-PD1 resistant metastatic non-small cell lung cancer (NSCLC) in a humanized mouse model
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PITAR , a DNA damage-inducible Cancer/Testis long noncoding RNA, inactivates p53 by binding and stabilizing TRIM28 mRNA
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Dual Targeting of Histone Deacetylases and MYC as Potential Treatment Strategy for H3-K27M Pediatric Gliomas
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Timing of treatment shapes the path to androgen receptor signaling inhibitor resistance in prostate cancer
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