Cancer Biology
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Arginase 1 is a key driver of immune suppression in pancreatic cancer
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CD81 partners with CD44 in promoting exosome biogenesis, tumor cluster formation, and lung metastasis in triple negative breast cancer
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Adrenal cortex size, homeostasis and tumorigenesis is regulated by gonadal hormones via androgen receptor/β-catenin signalling crosstalk
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Pancreatic tumors activate arginine biosynthesis to adapt to myeloid-driven amino acid stress
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The CIC-ERF co-deletion underlies fusion independent activation of ETS family member, ETV1, to drive prostate cancer progression
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RAF conformational autoinhibition and 14-3-3 proteins promote paradoxical activation
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ONC201/TIC10 enhances durability of mTOR inhibitor everolimus in metastatic ER+ breast cancer
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MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer
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eRNA profiling uncovers the enhancer landscape of oesophageal adenocarcinoma and reveals new deregulated pathways
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GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis
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