Cell Biology
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Small disulfide loops in peptide hormones mediate self-aggregation and secretory granule sorting
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Mitoxantrone modulates a glycosaminoglycan-spike complex to inhibit SARS-CoV-2 infection
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Increased mTOR signaling, impaired autophagic flux and cell-to-cell viral transmission are hallmarks of SARS-CoV-2 infection
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Aging is associated with increased brain iron through brain-derived hepcidin expression
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Autophagy suppression by TORC1 maintains epithelial plasma membrane integrity and inhibits syncytium formation
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Pathogenic mutations in the chromokinesin KIF22 disrupt anaphase chromosome segregation
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A high throughput SEC23 functional interaction screen reveals a role for focal adhesion and extracellular matrix signalling in the regulation of COPII subunit SEC23A
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Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
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mTOR activation induces endolysosomal remodeling and nonclassical secretion of IL-32 via exosomes in inflammatory reactive astrocytes
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Proximity labeling identifies LOTUS domain proteins that promote the formation of perinuclear germ granules in C. elegans
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