Molecular Biology
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Two redundant ubiquitin-dependent pathways of BRCA1 localization to DNA damage sites
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Epigenetic rewriting at centromeric DNA repeats leads to increased chromatin accessibility and chromosomal instability
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The deubiquitinase Usp9x regulates PRC2-mediated chromatin reprogramming during mouse development
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Poly-ADP-ribosylation drives loss of protein homeostasis in ATM and Mre11 deficiency
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Changing and stable chromatin accessibility supports transcriptional overhaul during neural stem cell activation
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Recognition of cellular RNAs by the S9.6 antibody creates pervasive artefacts when imaging RNA:DNA hybrids
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Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the aggregation of other proteins
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Tousled-like kinase activity is required for transcriptional silencing and suppression of innate immune signaling
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SF3B1-targeted Splicing Inhibition Triggers Transcriptional Stress Response and Global Alterations in R-Loop Landscape
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Genome-wide molecular recording using Live-seq
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