Temporal Association Between Particulate Matter Pollution and Case Fatality Rate of COVID-19 in Wuhan, China

The Coronavirus (COVID-19) epidemic, which was first reported in December 2019 in Wuhan, China, has caused 3,314 death as of March 31, 2020 in China. This study aimed to investigate the temporal association between case fatality rate (CFR) of COVID-19 and particulate matter (PM) in Wuhan. We conducted a time series analysis to explore the temporal day-by-day associations. We found COVID-19 held higher case fatality rate with increasing concentrations of PM _2.5 and PM ₁₀ in temporal scale, which may affect the process of patients developed from mild to severe and finally influence the prognosis of COVID-19 patients.