Sensitivity of nasopharyngeal swabs and saliva for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

  1. Alainna J. Jamal
  2. Mohammad Mozafarihashjin
  3. Eric Coomes
  4. Jeff Powis
  5. Angel Xin Liu
  6. Aimee Paterson
  7. Sofia Anceva-Sami
  8. Shiva Barati
  9. Gloria Crowl
  10. Amna Faheem
  11. Lubna Farooqi
  12. Saman Khan
  13. Karren Prost
  14. Susan Poutanen
  15. Lily Yip
  16. Zoe Zhong
  17. Allison J. McGeer
  18. Samira Mubareka
  19. for the Toronto Invasive Bacterial Diseases Network COVID-19 Investigators
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Abstract

We enrolled 53 consecutive in-patients with COVID-19 at six hospitals in Toronto, Canada, and tested one nasopharyngeal swab/saliva sample pair from each patient for SARS-CoV-2. Overall, sensitivity was 89% for nasopharyngeal swabs and 77% for saliva (p=NS); difference in sensitivity was greatest for sample pairs collected later in illness.

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