Identification of immunodominant linear epitopes from SARS-CoV-2 patient plasma

  1. Lluc Farrera-Soler
  2. Jean-Pierre Daguer
  3. Sofia Barluenga
  4. Patrick Cohen
  5. Sabrina Pagano
  6. Sabine Yerly
  7. Laurent Kaiser
  8. Nicolas Vuilleumier
  9. Nicolas Winssinger
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Abstract

A novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) is the source of a current pandemic (COVID-19) with devastating consequences in public health and economic stability. Using a peptide array to map the antibody response of plasma from healing patients, we identified immunodominant linear epitopes corresponding to key proteolytic sites on the spike protein.

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