Is it safe to use a single ventilator for two or more patients?

Mechanical ventilation is essential in the SARS-CoV-2 pandemic context. Considering the limited availability of mechanical ventilators due to high costs increased by global demand, the use of a single ventilator for two or more patients has been encouraged. An experimental model that ventilates two test lungs with a single machine has been designed in order to measure possible asymmetries during parallel circuit ventilation under different lung compliance conditions. This paper reports a first assessment of the risks involved in ventilating two patients with a single machine. Since some volumetric differences are not monitored by the ventilator itself, the main risks involved are distension or alveolar collapse if used in actual patients that have different thoracopulmonary mechanics.