Dengue antibodies can cross-react with SARS-CoV-2 and vice versa -Antibody detection kits can give false-positive results for both viruses in regions where both COVID-19 and Dengue co-exist

  1. Himadri Nath
  2. Abinash Mallick
  3. Subrata Roy
  4. Soumi Sukla
  5. Keya Basu
  6. Abhishek De
  7. Subhajit Biswas
2 evaluations Published on
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Abstract

Five of thirteen Dengue antibody-positive serum samples, dated 2017 (pre-dating the COVID-19 outbreak) produced false-positive results in SARS-CoV-2 IgG/IgM rapid strip tests. Our results emphasize the importance of NAT and/or virus antigen tests to complement sero-surveillance for definitive diagnosis of COVID-19/Dengue in regions where both viruses are co-endemic.

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