Transplacental Transfer of SARS-CoV-2 Antibodies

  1. Dustin D. Flannery
  2. Sigrid Gouma
  3. Miren B. Dhudasia
  4. Sagori Mukhopadhyay
  5. Madeline R. Pfeifer
  6. Emily C. Woodford
  7. Jourdan E. Triebwasser
  8. Jeffrey S. Gerber
  9. Jeffrey S. Morris
  10. Madison E. Weirick
  11. Christopher M. McAllister
  12. Marcus J. Bolton
  13. Claudia P. Arevalo
  14. Elizabeth M. Anderson
  15. Eileen C. Goodwin
  16. Scott E. Hensley
  17. Karen M. Puopolo
1 evaluations Published on
Read the full article Related papers
This article on Sciety

Abstract

We measured SARS-CoV-2 antibody levels in serum samples from 1,471 mother/newborn dyads and found efficient transplacental transfer of SARS-CoV-2 IgG antibodies in 72 of 83 seropositive pregnant women. Transfer ratios >1.0 were observed among women with an asymptomatic SARS-CoV-2 infection as well as those with mild, moderate and severe COVID-19. Our findings demonstrate the potential for maternally-derived antibodies to provide neonatal protection from SARS-CoV-2 infection.

Related articles

Related articles are currently not available for this article.