Reliability and limits of transport-ventilators to safely ventilate severe patients in special surge situations

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Abstract

Background

Several Intensive Care Units (ICU) have been overwhelmed by the surge of COVID-19 patients thus necessitating to extend ventilation capacity outside the ICU where air and oxygen pressure are not always available. Transport ventilators requiring only O2 source may be used to deliver volume-controlled ventilation.

Objective

To evaluate the performances of four transport ventilators compared to an ICU ventilator simulating severe respiratory conditions.

Materials and methods

Two pneumatic transport ventilators, (Oxylog 3000, Draeger; Osiris 3, Air Liquide Medical Systems) and two turbine transport ventilators (Elisee 350, ResMed; Monnal T60, Air Liquide Medical Systems) were compared to an ICU ventilator (Engström Carestation – GE Healthcare) using a Michigan training test lung. We tested each ventilator with different set volumes Vtset (350, 450, 550 ml) and different compliances (20 or 50 ml/cmH2O) and a resistance of 15 cmH2 0/L/sec based on values recently described in COVID-19 Acute Respiratory Distress Syndrome. Volume error was measured, as well as the trigger time delay during assist-control ventilation simulating spontaneous breathing activity with a P0.1 of 4 cmH20.

Results

Grouping all conditions, the volume error was 2.9 ± 2.2 % for Engström Carestation; 3.6 ± 3.9 % for Osiris 3; 2.5 ± 2.1 % for Oxylog 3000; 5.4 ± 2.7 % for Monnal T60 and 8.8 ± 4.8 % for Elisee 350. Grouping all conditions, trigger delay was 42 ± 4 ms, 65 ± 5 ms, 151 ± 14 ms, 51 ± 6 and 64 ± 5 ms for Engström Carestation, Osiris 3, Oxylog 3000, Monnal T60 and Elisee 350, respectively.

Conclusions

In special surge situations such as COVID-19 pandemic, most transport ventilators may be used to safely deliver volume-controlled ventilation in locations where only oxygen pressure supply is available with acceptable volume accuracy. Performances regarding triggering function are generally acceptable but vary across ventilators.

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