Ready for a BASE jump? Do not neglect SARS-CoV-2 hospitalization and fatality risks in the middle-aged adult population

  1. Nathanael Lapidus
  2. Juliette Paireau
  3. Daniel Levy-Bruhl
  4. Xavier de Lamballerie
  5. Gianluca Severi
  6. Mathilde Touvier
  7. Marie Zins
  8. Simon Cauchemez
  9. Fabrice Carrat
  10. the SAPRIS-SERO study group
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Abstract

Seroprevalence results coupled with surveillance data were used to estimate the SARS-CoV-2 infection hospitalization (IHR) and infection fatality ratios (IFR) in France. IHR and IFR were dramatically high in the very elderly (80-90 years: IHR: 30%, IFR: 11%), but also substantial in middle-aged adults (40-50 years: IHR: 1.2%, IFR: 0.05%).

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