Seroepidemiology of SARS-CoV-2 infections in an urban Nicaraguan population

  1. Fredman González
  2. Nadja A. Vielot
  3. Michael Sciaudone
  4. Christian Toval-Ruíz
  5. Lakshmanane Premkumar
  6. Lester Gutierrez
  7. Edwing Centeno Cuadra
  8. Patricia Blandón
  9. Aravinda M. de Silva
  10. Rebecca Rubinstein
  11. Natalie Bowman
  12. Sylvia Becker-Dreps
  13. Filemon Bucardo
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Abstract

In a Nicaraguan population-based cohort, SARS-CoV-2 seroprevalence was 34%, with higher prevalence in children compared to adults. Having a seropositive household member was associated with a two-fold probability of individual seropositivity, suggesting a role for household transmission. Co-morbidities and preventive behaviors were not associated with SARS-CoV-2 seroprevalence.

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