Levels of produced antibodies after vaccination with mRNA vaccine; effect of previous infection with SARS-CoV-2

  1. Theocharis Konstantinidis
  2. Stavroula Zisaki
  3. Ioannis Mitroulis
  4. Eleni Konstantinidou
  5. Eftychia G. Kontekaki
  6. Gioulia Romanidoui
  7. Alexandros Karvelas
  8. Ioanna Nanousi
  9. Leonidas Lazidis
  10. Dimitrios Cassimos
  11. Christina Tsigalou
  12. George Martinis
  13. Maria Panopoulou
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Abstract

The aim of this study was to estimate the immunogenic effect of mRNA vaccine against SARS-CoV-2. This study included 510 participants who received mRNA vaccine. The measurement of anti-Covid-19 antibodies was performed using the Abbott SARS-CoV-2 IgG quantitative assay (Abbott). Overall, mean title of anti-Spike antibodies was 19319.2±1787.5 AU/ml. Vaccination induced a robust immunogenic response in previous infected with SARS-CoV-2 compared. Additionally, individuals that were asymptomatic after vaccination produced lower levels of antibodies compared to feverish individuals. In conclusion, remarkable high level of anti-Spike Covid-19 antibodies was found after vaccination.

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