Antibody responses to BNT162b2 mRNA COVID-19 vaccine in 2,015 healthcare workers in a single tertiary referral hospital in Japan

  1. Takahiro Kageyama
  2. Kei Ikeda
  3. Shigeru Tanaka
  4. Toshibumi Taniguchi
  5. Hidetoshi Igari
  6. Yoshihiro Onouchi
  7. Atsushi Kaneda
  8. Kazuyuki Matsushita
  9. Hideki Hanaoka
  10. Taka-Aki Nakada
  11. Seiji Ohtori
  12. Ichiro Yoshino
  13. Hisahiro Matsubara
  14. Toshinori Nakayama
  15. Koutaro Yokote
  16. Hiroshi Nakajima
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Abstract

We measured antibody responses in 2,015 healthcare workers who were receiving 2 doses of BNT162b2 mRNA vaccine against SARS-CoV-2. The vast majority (99.9%) had either seroconversion or a substantial increase in antibody titer. A multivariate linear regression model identified predictive factors for antibody responses which may have clinical implications.

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