SARS-CoV-2 Delta variant of concern in Brazil - multiple introductions, communitary transmission, and early signs of local evolution

  1. José Patané
  2. Vincent Viala
  3. Loyze Lima
  4. Antonio Martins
  5. Claudia Barros
  6. Elaine Marqueze
  7. Jardelina Bernardino
  8. Debora Moretti
  9. Svetoslav Slavov
  10. Rafael Bezerra
  11. Evandra Rodrigues
  12. Elaine Santos
  13. Ricardo Brassaloti
  14. Raquel Cassano
  15. Pilar Mariani
  16. João Kitajima
  17. Bibiana Santos
  18. Patricia Assato
  19. Felipe Costa
  20. Mirele Poleti
  21. Jessika Lesbon
  22. Elisangela Chicaroni
  23. Cecilia Banho
  24. Lívia Sacchetto
  25. Marília Moraes
  26. Melissa Palmieri
  27. Fabiana Vilanova
  28. Maiara Martininghi
  29. Rejane Grotto
  30. Jayme Souza-Neto
  31. Marta Giovanetti
  32. Luiz Alcantara
  33. Maurício Nogueira
  34. Heidge Fukumasu
  35. Luiz Coutinho
  36. Rodrigo Calado
  37. Simone Kashima
  38. Raul Neto
  39. Dimas Covas
  40. Carolina Elias
  41. Sandra Coccuzzo
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Abstract

The dissemination of the Delta VOC in Brazil is still unclear, despite the frequent reports of isolated cases from different Brazilian states. In this report we characterize the dissemination of the Delta VOC in Brazil and where the introductions of this lineage fall within the global Delta phylogeny. We also examined the mutational profile of the largest clade within the Brazilian Delta VOCs, with a focus on samples which were obtained in the State of São Paulo, and especially in the city of São Paulo, the largest metropolis of South America, and a national and international transportation hub.

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