Acquired peripheral nerve injuries associated with severe COVID-19

  1. Colin K. Franz
  2. Nikhil K. Murthy
  3. George R. Malik
  4. Jean W. Kwak
  5. Dom D’Andrea
  6. Alexis R. Wolfe
  7. Ellen Farr
  8. Melanie A. Stearns
  9. Swati Deshmukh
  10. Jinny O. Tavee
  11. Fang Sun
  12. Kevin N. Swong
  13. Leslie Rydberg
  14. R. James Cotton
  15. Lisa F. Wolfe
  16. James M. Walter
  17. John M. Coleman
  18. John A. Rogers
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Abstract

We diagnosed 66 peripheral nerve injuries in 34 patients who survived severe COVID-19. We combine our latest data with published case series re-analyzed here (117 nerve injuries; 58 patients) to provide a comprehensive accounting of lesion sites. The most common are ulnar (25.1%), common fibular (15.8%), sciatic (13.1%), median (9.8%), brachial plexus (8.7%) and radial (8.2%) nerves at sites known to be vulnerable to mechanical loading. Protection of peripheral nerves should be prioritized in the care of COVID-19 patients. To this end, we report proof of concept data of a wearable, wireless pressure sensor to provide real time monitoring in the intensive care unit setting.

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