Pre-pandemic SARS-CoV-2 serological reactivity in rural malaria-experienced Cambodians

  1. Jessica Manning
  2. Irfan Zaidi
  3. Chanthap Lon
  4. Luz Angela Rosas
  5. Jae-Keun Park
  6. Aiyana Ponce
  7. Jennifer Bohl
  8. Sophana Chea
  9. Maria Karkanitsa
  10. Sokunthea Sreng
  11. Huy Rekol
  12. Char Meng Chour
  13. Dominic Esposito
  14. Jeffery K. Taubenberger
  15. Matthew J. Memoli
  16. Kaitlyn Sadtler
  17. Patrick E. Duffy
  18. Fabiano Oliveira
1 evaluations Published on
Read the full article Related papers
This article on Sciety

Abstract

Greater Mekong inhabitants are exposed to pathogens, zoonotic and otherwise, that may influence SARS-CoV-2 seroreactivity. A pre-pandemic (2005 to 2011) serosurvey of from 528 malaria-experienced Cambodians demonstrated higher-than-expected (up to 13.8 %) positivity of non-neutralizing IgG to SARS-CoV-2 spike and RBD antigens. These findings have implications for interpreting large-scale serosurveys.

Article Summary Line

In the pre-COVID19 pandemic years of 2005 to 2011, malaria experienced Cambodians from rural settings had higher-than-expected seroreactivity to SARS-CoV-2 spike and receptor binding domain proteins.

Related articles

Related articles are currently not available for this article.