CoWWAn: Model-based assessment of COVID-19 epidemic dynamics by wastewater analysis

We present COVID-19 Wastewater Analyser (CoWWAn) to reconstruct the epidemic dynamics from SARS-CoV-2 viral load in wastewater. As demonstrated for various regions and sampling protocols, this mechanistic model-based approach quantifies the case numbers, provides epidemic indicators and accurately infers future epidemic trends. In situations of reduced testing capacity, analysing wastewater data with CoWWAn is a robust and cost-effective alternative for real-time surveillance of local COVID-19 dynamics.