Analytical evaluation of thirty-two SARS-CoV-2 lateral flow antigen tests demonstrates sensitivity remains with the SARS-CoV-2 Gamma lineage

  1. Konstantina Kontogianni
  2. Daisy Bengey
  3. Dominic Wooding
  4. Kate Buist
  5. Caitlin Greenland-Bews
  6. Christopher T. Williams
  7. Margaretha de Vos
  8. Camille Escadafal
  9. Emily R. Adams
  10. Thomas Edwards
  11. Ana I. Cubas-Atienzar
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Abstract

The limit of detection (LOD) of thirty-two antigen lateral flow tests (Ag-RDT) were evaluated with the SARS-CoV-2 Gamma variant. Twenty-eight of thirty-two Ag-RDTs exceeded the World Health Organization criteria of an LOD of 1.0×106 genome copy numbers/ml and performance was equivalent as with the 2020 B.1 lineage and Alpha variant.

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