mRNA COVID-19 vaccine effectiveness against SARS-CoV-2 infection in a prospective community cohort, rural Wisconsin, November 2020-December 2021

  1. Huong Q McLean
  2. David L McClure
  3. Jennifer P King
  4. Jennifer K Meece
  5. David Pattinson
  6. Gabriele Neumann
  7. Yoshihiro Kawaoka
  8. Melissa A Rolfes
  9. Edward A Belongia
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Abstract

Reduced COVID-19 vaccine effectiveness (VE) has been observed with increasing predominance of the Delta variant. In a prospective rural community cohort of 1265 participants, VE against symptomatic and asymptomatic SARS-CoV-2 infection was 56% for mRNA COVID-19 vaccines.

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