Analysis of cutoff point estimation for determining seropositivity in the context of SARS-CoV-2 infections

In this work will apply mixture models based on distributions from the SMSN family to antibody data against four SARS-CoV-2 virus antigens. Furthermore, since the true infection status of individuals is known a priori , performance measures will be calculated for the methods proposed for cutoff point estimation such as sensitivity, specificity and accuracy. The results of a simulation study will also be presented.