Experimental infection of mink with SARS-COV-2 Omicron (BA.1) variant leads to symptomatic disease with lung pathology and transmission

  1. Jenni Virtanen
  2. Kirsi Aaltonen
  3. Kristel Kegler
  4. Vinaya Venkat
  5. Thanakorn Niamsap
  6. Lauri Kareinen
  7. Rasmus Malmgren
  8. Olga Kivelä
  9. Nina Atanasova
  10. Pamela Österlund
  11. Teemu Smura
  12. Antti Sukura
  13. Tomas Strandin
  14. Lara Dutra
  15. Olli Vapalahti
  16. Heli Nordgren
  17. Ravi Kant
  18. Tarja Sironen
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Abstract

We report an experimental infection of American mink with SARS-CoV-2 Omicron variant and show that minks remain virus RNA positive for days, develop clinical signs and histopathological changes, and transmit the virus to uninfected recipients warranting further studies and preparedness.

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