SARS-CoV-2 neutralizing antibodies in Chile after a vaccination campaign with five different schemes

  1. Ximena Aguilera
  2. Juan Hormazabal
  3. Cecilia Vial
  4. Lina Jimena Cortes
  5. Claudia Gonzalez
  6. Paola Rubilar
  7. Mauricio Apablaza
  8. Muriel Ramirez-Santana
  9. Gloria Icaza
  10. Loreto Nuñez-Franz
  11. Carla Castillo-Laborde
  12. Carolina Ramirez-Riffo
  13. Claudia Perez
  14. Ruben Quezada-Gate
  15. Macarena Said
  16. Pablo Vial
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Abstract

Using levels of neutralizing antibodies (nAbs), we evaluate the successful Chilean SARS-CoV-2 vaccine campaign, which combines technologies and heterologous boosters. In 120 randomly selected seropositive individuals from a population-based study, we conclude that the booster dose, regardless of vaccine technology or natural infection, and mRNA vaccines significantly improve nAbs response.

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