Boltz-1: Democratizing Biomolecular Interaction Modeling

This article has 0 evaluations Published on
Read the full article Related papers
This article on Sciety

Abstract

Understanding biomolecular interactions is fundamental to advancing fields like drug discovery and protein design. In this paper, we introduce B<sc>oltz</sc>-1, an open-source deep learning model incorporating innovations in model architecture, speed optimization, and data processing achieving A<sc>lpha</sc>F<sc>old</sc>3-level accuracy in predicting the 3D structures of biomolecular complexes. B<sc>oltz</sc>-1 demonstrates a performance on-par with state-of-the-art commercial models on a range of diverse benchmarks, setting a new benchmark for commercially accessible tools in structural biology. By releasing the training and inference code, model weights, datasets, and benchmarks under the MIT open license, we aim to foster global collaboration, accelerate discoveries, and provide a robust platform for advancing biomolecular modeling.

Related articles

Related articles are currently not available for this article.