International recommendations for sleep and circadian research in aging and Alzheimer’s disease: a Delphi consensus study

  1. Claire André
  2. Laura Stankeviciute
  3. Johannes C Michaelian
  4. Inga M Antonsdottir
  5. Ruth M Benca
  6. Elizabeth J Coulthard
  7. Angela L D’Rozario
  8. Derk-Jan Dijk
  9. Sandra Gimenez
  10. Maurizio Gorgoni
  11. Yue Leng
  12. Brendan P Lucey
  13. Matthew P Pase
  14. Stephanie R Rainey-Smith
  15. Ivana Rosenzweig
  16. Adam P Spira
  17. Joseph R Winer
  18. Géraldine Rauchs
  19. Sharon L Naismith
  20. Sleep and Circadian Rhythms Professional Interest Area of the International Society to Advance Alzheimer’s Research and Treatment (ISTAART)
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Abstract

Introduction

Research in the field of sleep, aging and dementia is rapidly growing. Consensus guidance is needed to facilitate high-quality research, comparability and consistency.

Methods

A modified Delphi consensus study was conducted by theSleep and Circadian Rhythms Professional Interest Areaof the International Society to Advance Alzheimer’s Research and Treatment (ISTAART) and an international panel of experts to establish recommendations for future research.

Result

After two voting rounds, the group determined by consensus (1) the most relevant sleep and circadian features to assess in the context of aging and dementia research, (2) established recommendations on data acquisition and report for future studies, and (3) identified high-priority future directions.

Discussion

This expert consensus study provides guidance to develop high-quality sleep and circadian research in the context of aging and dementia. Similar recommendations will need to be established for clinical practice.

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