Atmospheric pattern correlates of human brain structure

Climate change increasingly impacts human health, yet its neurobiological effects remain poorly understood. Analysing structural neuroimaging data of 30,831 UK participants (4,294 with follow-up assessments), we show that ambient weather conditions (warm, sunny, low precipitation and wind speed) associate with brain structure variations that exceed contributions from Alzheimer’s disease genetic risk scores and self-reported mental health. These findings establish atmospheroc patterns as measurable environmental correlates of brain structure and reveal new pathways for understanding climate-brain interactions.