A randomized controlled trial (RCT) of Juniver, a new digital intervention for eating disorder symptoms

Juniver is an app-based program for eating disorder symptoms combining neuroscience, CBT, an AI support tool configured specifically for eating disorder symptoms, and moderated peer groups. This study evaluated Juniver’s efficacy using a randomized controlled trial design, assigning participants aged ≥16-years to Juniver immediately or after 12-weeks (wait-list control). Participants completed measures of eating disorder symptoms, depression, anxiety, psychosocial impairment, and stress at baseline and 4-, 8-, 12-, 16-, 20 -and 24-weeks. The primary outcome was global eating disorder symptomatology at 12-weeks. Analyses used baseline-adjusted mixed models for repeated measures, with restricted maximum likelihood. N=357 participants were randomized. Juniver participants (n=179) showed significantly greater reductions than control (n=178) on the primary outcome as well as binge eating, clinical impairment, depression and anxiety. Adverse events were n=18 for Juniver and n=32 for control, including 1x control participant emergency hospitalization. Results support the efficacy and safety of Juniver for eating disorder symptoms.