Bibliometric Analysis of Nanotechnology Research for MRSA Treatment (2007–2025)

Antibiotic resistance in bacteria remains one of the most urgent global health challenges, as emphasized by the World Health Organization. In response, beyond the discovery of new antibiotics, researchers have increasingly turned to nanotechnology to design advanced antibacterial agents capable of targeting resistant strains or enhancing the efficacy of existing therapies, for example by employing nanocarrier-based delivery systems. Methicillin-resistant Staphylococcus aureus (MRSA) represents a particularly critical pathogen due to the difficulties associated with its treatment. In this study, we conducted a bibliometric analysis of research published between 2007 and 2025 on nanotechnology-enabled strategies for MRSA treatment. Data were collected from the Scopus database and visualized using VOSviewer software to map research networks and trends. Our findings reveal that China leads global output in this domain, with Chinese institutions consistently at the forefront. Notably, 70% of the top ten contributing countries are located in Asia, underscoring the region’s dominant role in advancing this field. The publication trend demonstrates an extraordinary increase of nearly 9,000% from 2007 to 2024, reflecting the accelerating momentum of research activity. Emerging topics such as nanozymes , chemodynamic therapy , and photothermal platforms have attracted significant attention, highlighting their potential to overcome current therapeutic limitations. Taken together, these results indicate that nanoscience is rapidly reshaping the landscape of antimicrobial research, and its continued advancement promises to deliver innovative solutions for combating MRSA and other antibiotic-resistant pathogens.