In Vitro Biological Characterization of Titanium Alloys TNTM and TNHF as Potential Biomaterials for Bone Tissue Engineering

Annually, worldwide, approximately 2.5 million biomaterials are used in orthopedics, with significant market growth. Orthopedic implants represent the largest share of this sector, accounting for approximately 80% of global use, with a major economic impact also in Brazil. The main metals used in orthopedic implants include titanium alloys. Titanium alloys have been used in the manufacture of medical devices and bone substitutes to improve the quality of life of the world’s population, given population aging and increased life expectancy. This work investigates the in vitro biological interaction related to the characterization of β-metastable titanium alloys TNTM (Ti-29Nb-13Ta-4Mo) and TNHF (Ti-16Nb-10Hf) for application in bone tissues, aiming at their use in medical applications.