Biochemistry
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Malaria parasites require a divergent heme oxygenase for apicoplast gene expression and biogenesis
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Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays
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A new class of receptors: Lipids regulate mammalian Gsα-stimulated adenylyl cyclase activities via their membrane anchors
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Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPARγ
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Crystal structure and catalytic mechanism of PL35 family glycosaminoglycan lyases with an ultrabroad substrate spectrum
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Structural insights into human propionyl-CoA carboxylase (PCC) and 3-methylcrotonyl-CoA carboxylase (MCC)
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Transcriptome-wide identification of 5-methylcytosine by deaminase and reader protein-assisted sequencing
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The intrinsically disordered N-terminus of SUMO1 is an intramolecular inhibitor of SUMO1 interactions
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Elucidating the kinetic and thermodynamic insight into regulation of glycolysis by lactate dehydrogenase and its impact on tricarboxylic acid cycle and oxidative phosphorylation in cancer cells
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Bioorthogonal labeling of chitin in pathogenic Candida species reveals biochemical mechanisms of hyphal growth and homeostasis
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