Biochemistry
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Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate
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Energetic and structural control of polyspecificity in a multidrug transporter
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Growth inhibitory factor/metallothionein-3 is a sulfane sulfur-binding protein
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The alternative oxidase reconfigures the larval mitochondrial electron transport system to accelerate growth and development in Drosophila melanogaster
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Targeted Protein Degradation by KLHDC2 Ligands Identified by High Throughput Screening
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One-carbon metabolism enzyme Ahcy is a redox sensor that modulates gene expression to protect against light stress-induced retinal degeneration
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Shifting the PPARγ conformational ensemble towards a transcriptionally repressive state improves covalent inhibitor efficacy
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In silico discovery of nanobody binders to a G-protein coupled receptor using AlphaFold-Multimer
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Fibroblast growth factor 21 regulates neuromuscular junction innervation through HDAC4 in denervation-induced skeletal muscle atrophy
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Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
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