Biophysics
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Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors
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The delayed kinetics of Myddosome formation explains why Aβ aggregates trigger TLR4 less efficiently than LPS
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Prediction of Ca2+binding site in proteins with a fast and accurate method based on statistical mechanics and analysis of crystal structures
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A parametrized two-domain thermodynamic model explains diverse mutational effects on protein allostery
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Dependence of Nucleosome Mechanical Stability on DNA Mismatches
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The French flag problem revisited: Creating robust and tunable axial patterns without global signaling
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LRMP inhibits cAMP potentiation of HCN4 channels by disrupting intramolecular signal transduction
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Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse
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Metric Ion Classification (MIC): A deep learning tool for assigning ions and waters in cryo-EM and x-ray crystallography structures
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Cyclic muscle contractions reinforce the acto-myosin motors and mediate the full elongation of C. elegans embryo
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