Biophysics
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The αC-β4 loop controls the allosteric cooperativity between nucleotide and substrate in the catalytic subunit of protein kinase A
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Some mechanistic underpinnings of molecular adaptations of SARS-COV-2 spike protein by integrating candidate adaptive polymorphisms with protein dynamics
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Mitosis sets nuclear homeostasis of cancer cells under confinement
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Structural insights into the orthosteric inhibition of P2X receptors by non-ATP-analog antagonists
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Microtubules under mechanical pressure can breach dense actin networks
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Diffusive mediator feedback explains the health-to-disease transition of skin inflammation
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Constitutive activity of ionotropic glutamate receptors via hydrophobic substitutions in the ligand-binding domain
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A novel bivalent interaction mode underlies a non-catalytic mechanism for Pin1-mediated Protein Kinase C regulation
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Optical mapping of ground reaction force dynamics in freely behaving Drosophila melanogaster larvae
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Cryo-EM structure of Slo1 with the auxiliary γ1 subunit suggests mechanism of depolarization-independent activation
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