Biophysics
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Zn2+potentiation of OTOP proton channels identifies structural elements of the gating apparatus
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A pH-dependent cluster of charges in a conserved cryptic pocket on flaviviral envelopes
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PAR recognition by PARP1 regulates DNA-dependent activities and independently stimulates catalytic activity of PARP1
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Room-temperature crystallography reveals altered binding of small-molecule fragments to PTP1B
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Timeline of changes in spike conformational dynamics in emergent SARS-CoV-2 variants reveal progressive stabilization of trimer stalk and enhanced NTD dynamics
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DNAJA2 and Hero11 mediate similar conformational extension and aggregation suppression of TDP-43
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Gating interactions steer loop conformational changes in the active site of the L1 metallo-β-lactamase
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The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins
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Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains
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Dynamics of immune memory and learning in bacterial communities
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