Cancer Biology
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EccDNA formation is dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA double-strand break
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Rab11b-mediated integrin recycling promotes brain metastatic adaptation and outgrowth
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Epithelial-mesenchymal plasticity determines estrogen receptor positive (ER+) breast cancer dormancy and reacquisition of an epithelial state drives awakening
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SWI/SNF remains localized to chromatin in the presence of SCHLAP1
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Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments
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Hypoxia induces transcriptional and translational downregulation of the type I interferon (IFN) pathway in multiple cancer cell types
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Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth
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Axon-like protrusions promote small cell lung cancer migration and metastasis
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ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination deficient cells
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Cancer associated talin point mutations disorganise cell adhesion and migration
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