Genetics
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Genome-wide base editor screen identifies regulators of protein abundance in yeast
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An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR mediated homologous recombination
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Gallbladder adenocarcinomas undergo subclonal diversification and selection from precancerous lesions to metastatic tumors
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Intergenerational adaptations to stress are evolutionarily conserved, stress-specific, and have deleterious trade-offs
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Sperm mosaicism predicts transmission of de novo mutations to human blastocysts
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Variable paralog expression underlies phenotype variation
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Conditional GWAS of non-CG transposon methylation inArabidopsis thalianareveals major polymorphisms in five genes
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The ACF chromatin remodeling complex is essential for Polycomb repression
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Rapid and specific degradation of endogenous proteins in mouse models using auxin-inducible degrons
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Functional evolution of SARS-COV-2 Spike protein: adaptation on translation and infection via surface charge of spike protein
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