Pharmacology and Toxicology
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In search of nonlipogenic ABCA1 inducers (NLAI): precision coregulator TR-FRET identifies diverse signatures for LXR ligands
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Large-scale synthetic data enable digital twins of human excitable cells
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Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2
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4-aminoquinolines block heme iron reactivity and interfere with artemisinin action
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Magnesium isoglycyrrhizinate alleviates alcohol-associated liver disease through targeting HSD11B1
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Snake venom metalloproteinases are predominantly responsible for the cytotoxic effects of certain African viper venoms
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Single-cell transcriptomics identifies altered neutrophil dynamics and accentuated T-cell cytotoxicity in tobacco flavored e-cigarette exposed mouse lungs
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In vitro pharmacokinetics and pharmacodynamics of the diarylquinoline TBAJ-587 and its metabolites against Mycobacterium tuberculosis
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Nonspecific membrane bilayer perturbations by ivermectin underlie SARS-CoV-2 in vitro activity
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Mid-zone hepatocytes trade proliferation for survival via Atf4-Chop axis in early acute liver injury
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