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Pharmacology and Toxicology

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Showing page 10 of 22 pages of list content

  • Characterization of raloxifene as potential pharmacological agent against SARS-CoV-2 and its variants

    This article's authors
    1. Daniela Iaconis
    2. Carmine Talarico
    3. Candida Manelfi
    4. Maria Candida Cesta
    5. Mara Zippoli
    6. Francesca Caccuri
    7. Giulia Matusali
    8. Licia Bordi
    9. Laura Scorzolini
    10. Enrico Bucci
    11. Arnaldo Caruso
    12. Emanuele Nicastri
    13. Marcello Allegretti
    14. Andrea Rosario Beccari
    This article has 1 evaluations Latest evaluation on Nov 19, 2021 Published on Oct 24, 2021
  • μ-Theraphotoxin-Pn3a inhibition of Ca V 3.3 channels reveals a novel isoform-selective drug binding site

    This article's authors
    1. Jeffrey R. McArthur
    2. Jierong Wen
    3. Andrew Hung
    4. Rocio K. Finol-Urdaneta
    5. David J. Adams
    This article has 4 evaluations Latest evaluation on Nov 15, 2021 Published on Oct 4, 2021
  • Characterization of the Endogenous DAF-12 Ligand and Its Use as an Anthelmintic Agent inStrongyloides stercoralis

    This article's authors
    1. Zhu Wang
    2. Mi Cheong Cheong
    3. Jet Tsien
    4. Heping Deng
    5. Tian Qin
    6. Jonathan D. C. Stoltzfus
    7. Tegegn G. Jaleta
    8. Xinshe Li
    9. James B. Lok
    10. Steven A. Kliewer
    11. David J. Mangelsdorf
    This article has 4 evaluations Latest evaluation on Nov 12, 2021 Published on Sep 8, 2021
  • Covalent inhibition of endoplasmic reticulum chaperone GRP78 disconnects the transduction of ER stress signals to inflammation and lipid accumulation in diet-induced obese mice

    This article's authors
    1. Dan Luo
    2. Ni Fan
    3. Xiuying Zhang
    4. Fung Yin Ngo
    5. Jia Zhao
    6. Wei Zhao
    7. Min Huang
    8. Ding Li
    9. Yu Wang
    10. Jianhui Rong
    This article has 4 evaluations Latest evaluation on Nov 10, 2021 Published on Aug 20, 2021
  • Predicting drug polypharmacology from cell morphology readouts using variational autoencoder latent space arithmetic

    This article's authors
    1. Yuen Ler Chow
    2. Shantanu Singh
    3. Anne E. Carpenter
    4. Gregory P. Way
    This article has 8 evaluations Latest evaluation on Nov 7, 2021 Published on Sep 3, 2021
  • Bisphosphonate drugs have actions outside the skeleton and inhibit the mevalonate pathway in alveolar macrophages

    This article's authors
    1. Marcia A. Munoz
    2. Emma K. Fletcher
    3. Oliver P. Skinner
    4. Julie Jurczyluk
    5. Esther Kristianto
    6. Mark P. Hodson
    7. Shuting Sun
    8. Frank H. Ebetino
    9. David R. Croucher
    10. Philip M. Hansbro
    11. Jacqueline R. Center
    12. Michael J. Rogers
    This article has 5 evaluations Latest evaluation on Nov 1, 2021 Published on Aug 10, 2021
  • Repurposed nystatin to inhibit SARS-CoV-2 and mutants in the GI tract

    This article's authors
    1. Eszter Virág
    2. Dénes Seffer
    3. Ágota Pénzes-Hűvös
    4. Krisztina Varajti
    5. Géza Hegedűs
    6. István Jankovics
    7. József Péter Pallos
    This article has 1 evaluations Latest evaluation on Oct 23, 2021 Published on Oct 20, 2021
  • Discovery of Potent Triple Inhibitors of Both SARS-CoV-2 Proteases and Human Cathepsin L

    This article's authors
    1. Ittipat Meewan
    2. Jacob Kattoula
    3. Julius Y. Kattoula
    4. Danielle Skinner
    5. Pavla Fajtová
    6. Miriam A. Giardini
    7. Brendon Woodworth
    8. James H. McKerrow
    9. Jair Lage de Siqueira-Neto
    10. Anthony J. O’Donoghue
    11. Ruben Abagyan
    This article has 1 evaluations Latest evaluation on Oct 23, 2021 Published on Oct 20, 2021
  • Oral Lisinopril Raises Tissue Levels of ACE2, the SARS-CoV-2 Receptor, in Healthy Male and Female Mice

    This article's authors
    1. Steven D. Brooks
    2. Rachel L. Smith
    3. Aline da Silva Moreira
    4. Hans C. Ackerman
    This article has 1 evaluations Latest evaluation on Oct 23, 2021 Published on Feb 1, 2022
  • AUG-3387, a Human-Derived Monoclonal Antibody Neutralizes SARS-CoV-2 Variants and Reduces Viral Load from Therapeutic Treatment of Hamsters In Vivo

    This article's authors
    1. Christopher J. Emig
    2. Marco A. Mena
    3. Steven J. Henry
    4. Adela Vitug
    5. Christian John Ventura
    6. Douglas Fox
    7. Xammy Huu Nguyenla
    8. Haiyue Xu
    9. Chaeho Moon
    10. Sawittree Sahakijjpijarn
    11. Philip J. Kuehl
    12. David Revelli
    13. Zengrong Cui
    14. Robert O. Williams
    15. Dale J. Christensen
    This article has 1 evaluations Latest evaluation on Oct 17, 2021 Published on Oct 13, 2021
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