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Pharmacology and Toxicology

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Showing page 14 of 22 pages of list content

  • An expedited approach towards the rationale design of non-covalent SARS-CoV-2 main protease inhibitors with in vitro antiviral activity

    This article's authors
    1. Naoya Kitamura
    2. Michael Dominic Sacco
    3. Chunlong Ma
    4. Yanmei Hu
    5. Julia Alma Townsend
    6. Xiangzhi Meng
    7. Fushun Zhang
    8. Xiujun Zhang
    9. Adis Kukuljac
    10. Michael Thomas Marty
    11. David Schultz
    12. Sara Cherry
    13. Yan Xiang
    14. Yu Chen
    15. Jun Wang
    This article has 1 evaluations Latest evaluation on Dec 21, 2020 Published on Dec 20, 2020
  • Genetic determinants of COVID-19 drug efficacy revealed by genome-wide CRISPR screens

    This article's authors
    1. Wei Jiang
    2. Ailing Yang
    3. Jingchuan Ma
    4. Dawei Lv
    5. Mingxian Liu
    6. Liang Xu
    7. Chao Wang
    8. Zhengjin He
    9. Shuo Chen
    10. Jie Zhao
    11. Shishuang Chen
    12. Qi Jiang
    13. Yankai Chu
    14. Lin Shan
    15. Zhaocai Zhou
    16. Yun Zhao
    17. Gang Long
    18. Hai Jiang
    This article has 1 evaluations Latest evaluation on Oct 30, 2020 Published on Oct 27, 2020
  • SARS-CoV-2 inhibition in human airway epithelial cells using a mucoadhesive, amphiphilic chitosan that may serve as an anti-viral nasal spray

    This article's authors
    1. Krzysztof Pyrć
    2. Aleksandra Milewska
    3. Emilia Barreto Duran
    4. Paweł Botwina
    5. Rui Lopes
    6. Alejandro Arenas-Pinto
    7. Moutaz Badr
    8. Ryan Mellor
    9. Tammy L. Kalber
    10. Delmiro Fernandes-Reyes
    11. Andreas G. Schätzlein
    12. Ijeoma F. Uchegbu
    This article has 1 evaluations Latest evaluation on Dec 11, 2020 Published on Dec 10, 2020
  • Nelfinavir was predicted to be a potential inhibitor of 2019-nCov main protease by an integrative approach combining homology modelling, molecular docking and binding free energy calculation

    This article's authors
    1. Zhijian Xu
    2. Cheng Peng
    3. Yulong Shi
    4. Zhengdan Zhu
    5. Kaijie Mu
    6. Xiaoyu Wang
    7. Weiliang Zhu
    This article has 1 evaluations Latest evaluation on Aug 4, 2020 Published on Jan 28, 2020
  • Nucleotide Analogues as Inhibitors of Viral Polymerases

    This article's authors
    1. Jingyue Ju
    2. Shiv Kumar
    3. Xiaoxu Li
    4. Steffen Jockusch
    5. James J. Russo
    This article has 1 evaluations Latest evaluation on Aug 4, 2020 Published on Jan 31, 2020
  • Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms

    This article's authors
    1. Ana C. Puhl
    2. Ethan James Fritch
    3. Thomas R. Lane
    4. Longping V. Tse
    5. Boyd L. Yount
    6. Carol Queiroz Sacramento
    7. Tatyana Almeida Tavella
    8. Fabio Trindade MaranhĂŁo Costa
    9. Stuart Weston
    10. James Logue
    11. Matthew Frieman
    12. Lakshmanane Premkumar
    13. Kenneth H. Pearce
    14. Brett L. Hurst
    15. Carolina Horta Andrade
    16. James A. Levi
    17. Nicole J. Johnson
    18. Samantha C. Kisthardt
    19. Frank Scholle
    20. Thiago Moreno L. Souza
    21. Nathaniel John Moorman
    22. Ralph S. Baric
    23. Peter Madrid
    24. Sean Ekins
    This article has 1 evaluations Latest evaluation on Dec 3, 2020 Published on Dec 2, 2020
  • Discovery of rhodomyrtone as a broad-spectrum antiviral inhibitor with anti-SARS-CoV-2 activity

    This article's authors
    1. Wei Tang
    2. Jing Lu
    3. Qiao-Yun Song
    4. Man-Mei Li
    5. Li-Feng Chen
    6. Li-Jun Hu
    7. Shao-Min Yang
    8. Dong-Mei Zhang
    9. Ying Wang
    10. Yao-Lan Li
    11. Wen-Cai Ye
    This article has 1 evaluations Latest evaluation on Nov 17, 2020 Published on Nov 16, 2020
  • In Vitro Efficacy of “Essential Iodine Drops” Against Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2)

    This article's authors
    1. Köntös Zoltán
    This article has 1 evaluations Latest evaluation on Nov 11, 2020 Published on Nov 10, 2020
  • Discovery of a Novel Inhibitor of Coronavirus 3CL Protease for the Potential Treatment of COVID-19

    This article's authors
    1. Britton Boras
    2. Rhys M. Jones
    3. Brandon J. Anson
    4. Dan Arenson
    5. Lisa Aschenbrenner
    6. Malina A. Bakowski
    7. Nathan Beutler
    8. Joseph Binder
    9. Emily Chen
    10. Heather Eng
    11. Holly Hammond
    12. Jennifer Hammond
    13. Robert E. Haupt
    14. Robert Hoffman
    15. Eugene P. Kadar
    16. Rob Kania
    17. Emi Kimoto
    18. Melanie G. Kirkpatrick
    19. Lorraine Lanyon
    20. Emma K. Lendy
    21. Jonathan R. Lillis
    22. James Logue
    23. Suman A. Luthra
    24. Chunlong Ma
    25. Stephen W. Mason
    26. Marisa E. McGrath
    27. Stephen Noell
    28. R. Scott Obach
    29. Matthew N. O’Brien
    30. Rebecca O’Connor
    31. Kevin Ogilvie
    32. Dafydd Owen
    33. Martin Pettersson
    34. Matthew R Reese
    35. Thomas F. Rogers
    36. Michelle I. Rossulek
    37. Jean G. Sathish
    38. Norimitsu Shirai
    39. Claire Steppan
    40. Martyn Ticehurst
    41. Lawrence W. Updyke
    42. Stuart Weston
    43. Yuao Zhu
    44. Jun Wang
    45. Arnab K. Chatterjee
    46. Andrew D. Mesecar
    47. Matthew B. Frieman
    48. Annaliesa S. Anderson
    49. Charlotte Allerton
    This article has 1 evaluations Latest evaluation on Sep 16, 2020 Published on Feb 12, 2021
  • Therapeutic Drugs Targeting 2019-nCoV Main Protease by High-Throughput Screening

    This article's authors
    1. Yan Li
    2. Jinyong Zhang
    3. Ning Wang
    4. Haibo Li
    5. Yun Shi
    6. Gang Guo
    7. Kaiyun Liu
    8. Hao Zeng
    9. Quanming Zou
    This article has 1 evaluations Latest evaluation on Aug 4, 2020 Published on Jan 30, 2020
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