Pharmacology and Toxicology
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Blockade of SARS-CoV-2 infection in vitro by highly potent PI3K-α/mTOR/BRD4 inhibitor
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Antidepressant and antipsychotic drugs reduce viral infection by SARS-CoV-2 and fluoxetine show antiviral activity against the novel variants in vitro
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Cytotoxicity evaluation of chloroquine and hydroxychloroquine in multiple cell lines and tissues by dynamic imaging system and PBPK model
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AT-527 is a potent in vitro replication inhibitor of SARS-CoV-2, the virus responsible for the COVID-19 pandemic
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Computationally prioritized drugs inhibit SARS-CoV-2 infection and syncytia formation
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Broad-Spectrum, Patient-Adaptable Inhaled Niclosamide-Lysozyme Particles are Efficacious Against Coronaviruses in Lethal Murine Infection Models
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Database for drug metabolism and comparisons, NICEdrug.ch, aids discovery and design
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Decoding the Cure-all Effects of Ginseng
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SQ3370, the first clinical click chemistry-activated cancer therapeutic, shows safety in humans and translatability across species
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Selective inhibitors of JAK1 targeting a subtype-restricted allosteric cysteine
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