Pharmacology and Toxicology
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Preserved efficacy and reduced toxicity with intermittent linezolid dosing in combination with bedaquiline and pretomanid in a murine TB model
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Towardin vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia
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Applications of Machine Learning in Decision Analysis for Dose Management for Dofetilide
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Application of thein vivooxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity
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Targeting host glycolysis as a strategy for antimalarial development
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Liver-Chip: Reproducing Human and Cross-Species Toxicities
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Effective buprenorphine use and tapering strategies: Endorsements and insights by people in recovery from opioid use disorder on a Reddit forum
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Comparison of morphine, oxycodone and the biased MOR agonist SR-17018 for tolerance and efficacy in mouse models of pain
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Complex versus simple models: ion-channel cardiac toxicity prediction
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