Pharmacology and Toxicology
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Assessing drug safety by identifying the axis of arrhythmia in cardiomyocyte electrophysiology
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Sophocarpine inhibits TRP channels to produce anti-pruritic and analgesic effects in a mouse model of inflammatory itch and pain
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Metabolomic profiling reveals effects of marein on energy metabolism in HepG2 cells
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Discovery of a new activator of Slack potassium channels with robust efficacy in models of histamine-independent and chronic itch
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Discovery and biological evaluation of a potent small molecule CRM1 inhibitor for its selective ablation of extranodal NK/T cell lymphoma
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A novel triptolide analog downregulates NF-κB and induces mitochondrial apoptosis pathways in human pancreatic cancer
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Death by a Thousand Cuts – Combining Kinase Inhibitors for Selective Target Inhibition and Rational Polypharmacology
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Optical Control of G-Actin with a Photoswitchable Latrunculin
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The G protein biased serotonin 5-HT 2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice
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The herbicide acetochlor causes lipid peroxidation by inhibition of glutathione peroxidase 4
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