Systems Biology
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Predictive nonlinear modeling of malignant myelopoiesis and tyrosine kinase inhibitor therapy
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Missense variant interaction scanning reveals a critical role of the FERM-F3 domain for tumor suppressor protein NF2 conformation and function
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De Novo multi-omics pathway analysis (DMPA) designed for prior data independent inference of cell signaling pathways
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ChemChaste: Simulating spatially inhomogenous biochemical reaction-diffusion systems for modelling cell-environment feedbacks
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Co-substrate pools can constrain and regulate pathway fluxes in cell metabolism
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Evolved bacterial resistance to the chemotherapy gemcitabine modulates its efficacy
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Evolutionary conservation of sequence motifs at sites of protein modification
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PhysiPKPD: A pharmacokinetics and pharmacodynamics module for PhysiCell
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Transcription-replication interactions reveal principles of bacterial genome regulation
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Proteome-wide systems genetics identifies UFMylation as a regulator of skeletal muscle function
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