• The Global Burden of Undiagnosed Congenital Heart Disease in Resource-Limited Settings: A Systematic Review of Diagnostic Gaps and Solutions

    1. Yasser Mohammed Abdo Ali Al-Shawki
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    Annotation by Yasser Mohamed AlShawki

    This systematic analysis bridges the socio-economic and infrastructural gaps preventing timely CHD intervention in LMICs. By mapping the systemic drivers of diagnostic neglect, the research transitions from burden identification to proposing a scalable, multi-sectoral implementation roadmap. It specifically explores the potential of telecardiology and task-shifting as transformative tools for global health reform. An essential read for policymakers and public health advocates focused on structural reform and reducing health inequity." Keywords: Global Health Equity, Structural Reform, LMIC healthcare, Telecardiology integration, Task-shifting, Multi-sectoral intervention, Public health strategy, Healthcare infrastructure, Socio-economic barriers, Pediatric health policy.

  • The Neuro-theological Nexus: Quantifying the Impact of Islamic Prayer (Salah) on Brainwave Coherence and Stress Biomarkers

    1. YASSER MOHAMMED ABDO ALI AL-SHAWKI
    2. YASSER MOHAMMED ABDO ALI AL-SHAWKI
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    Annotation by Yasser Mohamed AlShawki

    A pioneering scientific inquiry into the neuro-theological nexus, quantifying the physiological and neurological impact of Islamic prayer (Salah) on brainwave coherence and stress-related biomarkers. This study explores the intersection of spirituality and neuroscience, offering empirical data on how repetitive ritualistic movements and meditative states modulate cognitive function and autonomic nervous system activity. By bridging the gap between contemplative practice and quantitative physiological measurement, this research provides a novel perspective on the mind-spirit connection. A critical read for neuroscientists, psychologists, and clinicians interested in the therapeutic potential of ritualized mindfulness and neuro-theology in managing stress and mental well-being. Keywords: Neuro-theology, Islamic prayer, Salah, Brainwave coherence, Stress biomarkers, Neuro-physiology, Mind-spirit connection, Mindfulness-based interventions, Cognitive function, Autonomic nervous system, Ritualized meditation, Neuro-cardiology, Psychophysiology, Contemplative practice, Mental well-being, Quantitative physiological analysis, Spiritual health, Stress modulation.

  • The Global Burden and Diagnostic Challenges of Undiagnosed Congenital Heart Disease in Resource-Limited Settings: A Comprehensive Systematic Review From 2000 to 2025 of Diagnostic Gaps and Solutions

    1. YASSER MOHAMMED ABDO ALI AL-SHAWKI
    2. YASSER MOHAMMED ABDO ALI AL-SHAWKI
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    Annotation by Yasser Mohamed AlShawki

    A comprehensive systematic review addressing the critical health crisis of undiagnosed congenital heart disease (CHD) in resource-limited settings. By analyzing diagnostic gaps and global health metrics from 2000 to 2025, this research identifies the profound impact of equipment shortages, specialist scarcity, and socio-economic barriers on vulnerable pediatric populations. Beyond identifying these systemic challenges, the review provides an evidence-based implementation roadmap for scalable solutions, including early-stage screening protocols, telecardiology integration, and AI-driven triage systems. This work serves as a call to action for global health policymakers, pediatric cardiologists, and public health stakeholders to bridge the diagnostic divide and improve clinical outcomes for children worldwide. Keywords: Congenital Heart Disease (CHD), Global health burden, Resource-limited settings, Pediatric cardiology, Diagnostic gaps, Telecardiology, AI-triage, Early screening, Public health metrics, Systematic review, Healthcare accessibility, Medical infrastructure, Diagnostic infrastructure, Health equity, Pediatric healthcare outcomes, Clinical implementation roadmap, Undiagnosed heart disease, Global child health, Medical technology in low-resource settings.

  • Sodium-Glucose Cotransporter-2 Inhibitors and Cutaneous Adverse Reactions: A Systematic Review of Clinical Phenotypes, Time-to- Onset Profiles, and Management Strategies (2020–2026)

    1. Yasser Mohammed Abdo Ali Al-Shawki
    2. Ziryab M. Al-Shawki
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    Annotation by Yasser Mohamed AlShawki

    Beyond the glucose-lowering benefits: a critical clinical investigation into the often-overlooked cutaneous adverse reactions associated with SGLT2 inhibitors. This systematic review (2020–2026) bridges a major gap in modern pharmacovigilance by mapping phenotype-specific time-to-onset profiles for a wide spectrum of dermatological events, ranging from manageable pruritus to life-threatening conditions like Fournier’s gangrene and Bullous Pemphigoid. By providing evidence-based insights into clinical phenotypes and resolution strategies, this research serves as an essential roadmap for endocrinologists, dermatologists, and primary care physicians to enhance patient safety and refine risk stratification in the treatment of type 2 diabetes and cardio-renal protection. ​Keywords: ​SGLT2 inhibitors, Cutaneous adverse reactions (CARs), Systematic review, Pharmacovigilance, Type 2 diabetes management, Dermatological safety, Bullous pemphigoid, Fournier’s gangrene, SJS/TEN (Stevens-Johnson syndrome), Time-to-onset profiles, Phenotype-guided management, Evidence-based dermatology, Drug-induced skin eruptions, Cardio-renal protection, Clinical risk stratification, Drug safety monitoring, Therapeutic optimization, Clinical decision-making, PRISMA 2020 guidelines.