Pharmacology and Toxicology
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Validation and invalidation of SARS-CoV-2 papain-like protease inhibitors
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Brilacidin, a COVID-19 Drug Candidate, demonstrates broad-spectrum antiviral activity against human coronaviruses OC43, 229E and NL63 through targeting both the virus and the host cell
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Novel pectin from crude polysaccharide of Syzygium aromaticum against SARS-CoV-2 activities by targeting 3CLpro
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Characterization of raloxifene as potential pharmacological agent against SARS-CoV-2 and its variants
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μ-Theraphotoxin-Pn3a inhibition of CaV3.3 channels reveals a novel isoform-selective drug binding site
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Characterization of the Endogenous DAF-12 Ligand and Its Use as an Anthelmintic Agent inStrongyloides stercoralis
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Covalent inhibition of endoplasmic reticulum chaperone GRP78 disconnects the transduction of ER stress signals to inflammation and lipid accumulation in diet-induced obese mice
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Predicting drug polypharmacology from cell morphology readouts using variational autoencoder latent space arithmetic
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Bisphosphonate drugs have actions outside the skeleton and inhibit the mevalonate pathway in alveolar macrophages
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Repurposed nystatin to inhibit SARS-CoV-2 and mutants in the GI tract
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