Pharmacology and Toxicology
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Characterization of raloxifene as potential pharmacological agent against SARS-CoV-2 and its variants
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μ-Theraphotoxin-Pn3a inhibition of CaV3.3 channels reveals a novel isoform-selective drug binding site
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Characterization of the Endogenous DAF-12 Ligand and Its Use as an Anthelmintic Agent inStrongyloides stercoralis
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Covalent inhibition of endoplasmic reticulum chaperone GRP78 disconnects the transduction of ER stress signals to inflammation and lipid accumulation in diet-induced obese mice
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Predicting drug polypharmacology from cell morphology readouts using variational autoencoder latent space arithmetic
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Bisphosphonate drugs have actions outside the skeleton and inhibit the mevalonate pathway in alveolar macrophages
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Repurposed nystatin to inhibit SARS-CoV-2 and mutants in the GI tract
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Discovery of Potent Triple Inhibitors of Both SARS-CoV-2 Proteases and Human Cathepsin L
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Oral Lisinopril Raises Tissue Levels of ACE2, the SARS-CoV-2 Receptor, in Healthy Male and Female Mice
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AUG-3387, a Human-Derived Monoclonal Antibody Neutralizes SARS-CoV-2 Variants and Reduces Viral Load from Therapeutic Treatment of Hamsters In Vivo
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